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RESEARCH FELLOW
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Position Number: 1471258
Location: Ann Arbor, MI
Position Type: Laboratory and Research

RESEARCH FELLOW

Job Opening ID: 172255
Work Location: Ann Arbor Campus
Full Time/Part Time: Full-Time
Regular/Temporary: Regular
FLSA Status: Exempt
Organizational Group: Medical School
Department: Int Med-Cardiology
Posting Begin/End Date: 5/09/2019 6/08/2019
Salary:
Paid Time Off:
Career Interest: Research Fellows

Job Summary
A cardiovascular genomics lab is seeking talented Postdoctoral Research Fellow candidates for human genetics studies that we are extending into in vitro and animal models of vascular disease (fibromuscular dysplasia, arterial dissection and aneurysm, a primary manifestations of arterial fibroplasia and aberrant vascular remodeling). In the lab, we perform gene discovery studies using genome sequencing, GWAS and transcript expression profiling methods to understand both common and rare vascular diseases. We use in vitro cellular and in vivo models to assess the functional significance of our genomic discoveries, and currently we have novel findings which we are modeling. We are performing ribosomal translation affinity and purification analyses in our disease mouse models, to generate and refine hypotheses regarding the genetic mechanism of disease. Current genetic investigations are focused on vascular smooth muscle cell transcription, arterial extracellular matrix, and the vascular phenotype of specific diseases such as Neurofibromatosis. Our studies are closely tied to the clinic, with human tissue and blood samples from meticulously phenotyped patients and thus candidates can expect to gain exposure to human genetics and translational aspects of their research projects.

The laboratory has multiple NIH and non-NIH sources of funding.

Mission Statement
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Required Qualifications*
The Candidates should hold a Ph.D. and have publications in genomics, molecular genetics or vascular biology fields with an interest in human genetics, ideally with prior experience with mouse models. The ideal candidate is highly motivated to learn solid scientific methods and to write manuscripts and grant applications.

Background Screening
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.

To apply, visit http://careers.umich.edu/job_detail/172255/research_fellow